KLIINISEN TUTKIMUKSEN KESKUS (CRC)

 

Tieteelliset julkaisut 2009

(Impact Factor suluissa)

1. Ala-Korpela M, Soininen P, Savolainen MJ. Letter by Ala-Korpela et al regarding article, "Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women". Circulation 120(17):e149; author reply e150, 2009 (IF=14,595)

2. Bolszak M, Anttonen AK, Komulainen T, Hinttala R, Pakanen S, Sormunen R, Herva R, Lehesjoki AE, Majamaa K, Rantala H, Uusimaa J: Digenic mutations in severe myoclonic epilepsy of infancy. Epilepsy Res 85: 300-304, 2009 (IF=2,405)

3. ChouM-Y, FogelstrandL, HartvigsenK, HansenLF, WoelkersD, ShawPX, Choi J, Perkmann T. BäckhedF, Miller YI, Hörkkö S, CorrM, WitztumJL & Binder CJ. Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans. J Clin Invest 119: 1335-1349, 2009 (IF=16,559)

4. Haukkamaa L, Moilanen L, Kattainen A, Luoto R, Kähönen M, Leinonen M, Jula A, Kesäniemi YA, Kaaja R: Pre-eclempsia is a risk factor for carotid artery atherosclerosis. Cerebrovasc Dis 27:599-607, 2009 (IF=3.041)

5. Heiskanen A, Hirvonen T, Salo H, Impola U, Olonen A, Laitinen A, Tiitinen S, Natunen S, Aitio O, Miller-Podraza H, Wuhrer M, Deelder AM, Natunen J, Laine J, Lehenkari P, Saarinen J, Satomaa T, Valmu L: Glycomics of bone marrow-derived mesenchymal stem cells can be used to evaluate their cellular differentiation stage. Glycoconj J 26(3):367-84, 2009 (IF=1,743)

6. Heula AL, Sajanti J, Majamaa K: Procollagen propeptides in chronic subdural hematoma reveal sustained dural collagen synthesis after head injury. J Neurol 256: 66–71, 2009 (IF=2,536)

7. Hietaniemi M, Jokela M, Rantala M, Ukkola O, Vuoristo JT, Ilves M, Rysä J, Kesäniemi YA: The effect of a short-term hypocaloric diet on liver gene expression and metabolic risk factors in obese women. Nutr Metab and Cardiovasc Dis 19:177-183, 2009 (IF=3.565)

8. Hietaniemi M, Malo E, Jokela M, Santaniemi M, Ukkola O, Kesäniemi YA: The effect of energy restriction during pregnancy on obesity-related peptide hormones in rat offspring. Peptides 30:705-709, 2009 (IF=2.565)

9. Huilaja L, Hurskainen T, Autio-Harmainen H, Sormunen R, Tu H, Hofmann SC, Pihlajaniemi T, Bruckner-Tuderman L, Tasanen K. Glycine substitution mutations cause intracellular accumulation of collagen XVII and affect its post-translational modifications. J Invest Dermatol 129(9):2302-6, 2009 (IF=5,251)

10. Hukkanen J, Ukkola O, Savolainen MJ: Effects of low-dose liquorice alone or in combination with hydrochlorothiazide on the plasma potassium in healthy volunteers. Blood Press 26:1-4, 2009 (IF=1,625)

11. Jukkola-Vuorinen A, Rahko E, Vuopala K, Desmond R, Lehenkari P, Harris KW, Selander KS : Toll-Like Receptor-9 Expression Is Inversely Correlated with Estrogen Receptor Status in Breast Cancer. Innate Immun 1:59–68, 2009

12. Järvenpää J, Vuoristo JT, Santaniemi M, Ukkola O, Savolainen E-R, Jääskeläinen M, Tapanainen J, Kesäniemi A, Ryynänen M: Adiponectin induced placental cell apoptosis could be mediated via the ADIPOR1-receptor in pre-eclampsia with IUGR. J Perinatal Med 37:257-262, 2009 (IF=1.234)

13. Jääskeläinen M, Kyrönlahti A, Anttonen M, Nishi Y, Yanase T, Secchiero P, Zauli,   Tapanainen JS, Heikinheimo M, Vaskivuo TE: TRAIL pathway components and their putative role in granulosa cell apoptosis in the human ovary. Differentation 77:239-376, 2009 (IF=3,180)

14. Kaarteenaho-Wiik R, Paakko P, Sormunen R: Ultrastructural features of lung fibroblast differentiation into myofibroblasts. Ultrastruct Pathol 33(1):6-15, 2009 (IF=0,768)

15. Kaarteenaho-Wiik R, Soini Y: Claudin-1, -2, -3, -4, -5, and -7 in usual interstiatial pneumonia and sarcoidosis. J Histochem Cytochem 57(3):187-95, 2009 (IF=2,823)

16. Kangas-Kontio T, Tapanainen JM, Huikuri H, Savolainen E-R, Päivänsalo M, Kauma H, Kesäniemi YA, Savolainen MJ, Kakko S: Variation in the vascular endothelial growth factor gene, carotid intima-media thickness and the risk of acute myocardial infarction. Scand J Clin Lab Invest 69:335-343, 2009 (IF=1.363)

17. Kangas-Kontio T, Vavuli S, Kakko SJ, Penna J, Savolainen ER, Savolainen MJ, Liinamaa MJ: Polymorphism of the manganese superoxide dismutase gene but not of vascular endothelial growth factor gene is a risk factor for diabetic retinopathy.Br J Ophthalmol 93(10):1401-6, 2009 (IF=2,859)

18. Kankaanpää J, Turunen SP, Moilanen V, Hörkkö S, Remes AM: Cerebrospinal fluid antibodies to oxidized LDL are increased in Alzheimer’s disease. Neurobiol Dis 33(3):467-72, 2009 (IF=4,852)

19. Kastarinen H, Hörkkö S, Kauma H, Karjalainen A, Savolainen MJ, Kesäniemi YA: Low-density lipoprotein clearance in patients with chronic renal failure. Nephrol Dial Transplant 24:2131-2135, 2009 (IF=3.568)

20. Kastarinen H, Kesäniemi YA, Ukkola O: Leptin and lipid metabolism in chronic kidney failure. Scand J Clin Lab Invest 69:401-408, 2009 (IF=1.363)

21. Kastarinen H, Ukkola O, Kesäniemi YA: Glomerular filtration rate is related to carotid intima-media thickness in middle-aged adults. Nephrol Dial Transplant 24:2767-2772, 2009 (IF=3.568)

22. Kellokoski E, Kummu O, Serpi R, Lehenkari P, Ukkola O, Kesäniemi YA, Hörkkö S: Ghrelin vaccination decreases plasma MCP-1 level in LDLR (-/-)- mice. Peptides 30:2292-2300, 2009 (IF=2.565)

23. Kellokoski E, Kunnari A, Jokela M, Mäkelä S, Kesäniemi YA, Hörkkö S: Ghrelin and obestatin modulate early atherogenic processes on cells: enhancement of monocyte adhesion and oxidized low-density lipoprotein binding. Metabolism 58:1572-1580, 2009 (2.920)

24. Keränen AM, Savolainen MJ, Reponen AH, Kujari ML, Lindeman SM, Bloigu RS, Laitinen JH: The effect of eating behavior on weight loss and maintenance during a lifestyle intervention. Prev Med 49(1):32-8, 2009 (IF=2,757)

25. Kesäniemi YA, Salomaa V: Sairauksien ehkäisy; Sepelvaltimotauti. Verkkojulkaisu. http://www.terveyskirjasto.fi/terveyskirjasto/tk.koti?p_artikkeli=seh00004&p_teos=seh&p_selaus=8896 Artikkelin tunnus: seh00004 (003.003). Kustannus Oy Duodecim 19.1.2009

26. Koskela S, Lehtonen S, Santala M, Venhola M, Parpala-Spårman T, Lehenkari P: 17beta-estradiol induces the proliferation of the in vitro cultures human urothelium. Scand J Urol Nephrol 43(3):179-85, 2009 (IF=0,909)

27. Koukkunen H, Lehto S, Salomaa V, Ketonen M, Immonen-Räihä P, Kärjä-Koskenkari P, Mustonen J, Airaksinen J, Lehtonen A, Havulinna A, Kesäniemi YA, Pyörälä K, FINAMI-tutkimusryhmä: FINAMI-tutkimus: Vanhusten sepelvaltimotauti kuormittaa merkittävästi terveydenhoitojärjestelmää. Suomen Lääkärilehti 64:795-802, 2009

28. Krüger J, Kaivorinne AL, Udd B, Majamaa K, Remes AM: Low prevalence of progranulin mutations in Finnish patients with frontotemporal lobar degeneration. Eur J Neurol 16(1):27-30, 2009 (IF=2,723)

29. Kumpula LS, Mäkelä SM, Mäkinen V-P, Karjalainen A, Liinamaa JM, Kaski K, Savolainen MJ, Hannuksela ML, Ala-Korpela M.Characterization of metabolic interrelationships and in silico phenotyping of lipoprotein particles using self-organizing maps.J Lipid Res 51(2):431-9, 2009 (IF=4,409)

30. Kunnari A, Savolainen E-R, Ukkola O, Kesäniemi YA, Jokela M: The expression of human resistin in different leucocyte lineages is modulated by LPS and TNFa. Regul Pept 157:57-63, 2009 (IF=2.276)

 31. La Marca A, Broekmans FJ, Volpe A, Fauser BC, Macklon NS; ESHRE Special Interest Group for Reproductive Endocrinology-AMH Round Table. Anti-Mullerian hormone (AMH): what do we still need to know? Hum Reprod 24:2264-2275, 2009 (IF=3,773)

32. Leskelä HV, Kuorilehto T, Risteli J, Koivunen J, Nissinen M, Peltonen S, Kinnunen P, Messiaen L, Lehenkari P, Peltonen J: Congenital pseudarthrosis of neurofibromatosis type 1: impaired osteoblast differentiation and function and altered NF1 gene expression. Bone (2):243-50, 2009 (IF=4,145)

33.  Leskelä P, Ukkola O, Vartiainen J, Rönnemaa T, Kaprio J, Bouchard C, Kesäniemi YA: Fasting plasma total ghrelin concentrations in monozygotic twins discordant for obesity. Metabolism 58:174-179, 2009 (IF=2.920)

34. Liisanantti MK, Savolainen MJ: Phosphatidylethanol mediates its effects on the vascular endothelial growth factor via HDL receptor in endothelial cells. Alcohol Clin Exp Res 33(2):283-8, 2009 (IF=3,166)

35. Lindroos MM, Majamaa K, Tura A, Mari A, Kalliokoski KK, Taittonen MT, Iozzo P, Nuutila P: The m.3243A>G mutation in mitochondrial DNA leads to decreased insulin sensitivity in skeletal muscle and to progressive b-cell dysfunction. Diabetes 58: 543-549, 2009 (IF=8,398)

36. Lindroos MM, Borra R, Parkkola R, Virtanen S, Lepomäki V, Bucci M, Virta JR, Rinne J, Nuutila P, Majamaa K: Cerebral oxygen and glucose metabolism in patients with mitochondrial m.3243A>G mutation. Brain 132: 3274-3284, 2009 (IF=9,603)

37. Ling H, Waterworth DM, Stirnadel HA, Pollin TI, Barter PJ, Kesäniemi YA, Mahley RW, McPherson R, Waeber G, Bersot TP, Cohen JC, Grundy SM, Mooser VE, Mitchell BD: Genome-wide Linkage and Association Analyses to Identify Genes Influencing Adiponectin Levels: the GEMS Study. Obesity 17:737-744, 2009 (IF=2.762)

38. Luotola K, Pääkkönen R, Alanne M, Lanki T, Moilanen L, Surakka I, Pietilä A, Kähönen M, Nieminen MS, Kesäniemi YA, Peters A, Jula A, Perola M, Salomaa V for the Healt 2000 and AIRGENE Study Groups: Association of variation in the interleukin-1 gene family with diabetes and glucose homeostasis. J Clin Endocrin Metab 94:4575-4583, 2009 (IF=6.325)

39. Löfgren E, Pouta A, Wendt LV, Tapanainen J, Isojärvi JI, Järvelin MR: Epilepsy in northern Finland birth cohort 1966 with special reference to fertility. Epilepsy Behav 14:102-107, 2009 (IF=2,302)

40. Mäenpää J, Karjalainen A, Kaarteenaho R. Keuhkolöydökset systeemisessä lupus erytematosuksessa. Duodecim 2099-2105, 2009

41.  Mäkelä J, Anttila V, Ylitalo K, Takalo R, Lehtonen S, Mäkikallio T, Niemelä E, Dahlbacka S, Tikkanen J, Kiviluoma K, Juvonen T, Lehenkari P: Acute homing of bone marrow-derived mononuclear cells in intramyocardial vs. intracoronary transplantation. Scand Cardiovasc J 43(6): 366-373, 2009 (IF=0,908)

42. Niemi J, Mäkinen V-P, Heikkonen J, Tenkanen L, Hiltunen Y, Hannuksela ML, Jauhiainen M, Forsblom C, Taskinen M-R, Kesäniemi YA, Savolainen MS, Kimmo Kaski K, Groop P-H, Kovanen PT, Ala-Korpela M: Estimation of VLDL, IDL, LDL, HDL2, apoA-I and apoB from the Friedewald inputs – apoB and IDL, but not LDL, are associated with mortality in type 1 diabetes. Ann Med 41:451-461. 2009 (IF=5.435)

43. Niinimäki M, Ruokonen A, Tapanainen JS, Järvelä IY: Effect of mifepristone on the corpus luteum in early pregnancy. Ultrasound Obstet Gynecol 34:448-453, 2009 (IF=2,690)

44. Peltonen T, Taskinen P, Näpänkangas J, Leskinen H, Ohtonen P, Soini Y, Juvonen T, Satta J, Vuolteenaho O, Ruskoaho H: Increase in tissue endothelin-1 and ETA receptor levels in human aortic valve stenosis. Eur Heart J 30(2):242-9, 2009 (IF=8,917)

45. Puurunen J, Piltonen T, Jaakkola P, Ruokonen A, Morin-Papunen LC, Tapanainen JS: Adrenal androgen production capacity remains high up to menopause in women with polycystic ovary syndrome. J Clin Endocrinol Metab 94:1973-197, 2009 (IF=6,325)

46. Remes A, Leikola M, Majamaa K, Nikkanen M, Ruokonen LI, Rusanen M, Tapiola T, Ylikotila P, Vallittu AM, Pirttilä T. Use of CSF biomarkers in the diagnostics of memory diseases. Duodecim 125(20):2215-22, 2009

47. Richards JB, Waterworth D, O’Rahilly S, Hivert M-F, Loos RJF, Perry JRB, Tanaka T, Timpson NJ, Semple RK, Soranzo N, Song K, Rocha N, Grundberg E, Dupuis J, Florez JC, Langenberg C, Prokopenko I, Saxena R, Sladek R, Aulchenko Y, Evans D, Waeber G, Erdmann J, Burnett M-S, Sattar N, Devaney J, Willenborg C, Hingorani A, Witteman JCM, Vollenweider P, Glaser B, Hengstenberg C, Ferrucci L, Melzer D, Stark K, Deanfield J, Winogradow J, Grassl M, Hall AS, Egan JM, Thompson JR, Ricketts SL, König IR, Reinhard W, Grundy S, Wichmann H-E, Barter P, Mahley R, Kesäniemi YA, Rader DJ, Reilly MP, Epstein SE, Stewart AFR, van Duijn CM, Schunkert H, Burling K, Deloukas P, Pastinen T, Samani NJ, McPherson R, Smith GD, Frayling TM, Wareham NJ, Meigs JB, Mooser V, Spector TD, GIANT consortium: A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PloS Genetics 12:e1000768, 2009 (IF=8.883)

48. Riikola A, Sipilä K, Kähönen M, Jula A, Nieminen MS, Moilanen L, Kesäniemi YA, Lehtimäki T, Hulkkonen J: Interleukin-6 promoter polymorphism and cardiovascular risk factors: The Health 2000 Survey. Atherosclerosis 207:466-470, 2009 (IF=4.601)

49.  Seppänen AO, Pikkarainen M, Hartikainen P, Hofmann SC, Majamaa K, Alafuzoff I: Expression of collagen XVII and ubiquitin-binding protein p62 in motor neuron disease. Brain Res 1247: 171-177, 2009 (IF=2,494)

50. Sipilä K, Moilanen L, Nieminen T, Reunanen A, Jula A, Salomaa V, Kaaja R, Kukkonen-Harjula K, Lehtimäki T, Kesäniemi YA, Koivistoinen T, Nieminen MS, Tuomilehto J, Kähönen M: Metabolic syndrome and carotid intima media thickness in the Health 2000 Survey. Atherosclerosis 204:276-81, 2009 (IF=4.601)

51. Soininen P, Kangas AJ, Würtz P, Tukiainen T, Tynkkynen T, Laatikainen R, Järvelin MR, Kähönen M, Lehtimäki T, Viikari J, Raitakari OT, Savolainen MJ, Ala-Korpela M: High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism. Analyst 134(9):1781-5, 2009 (IF=3,761)

52. Strengell T, Uhari M, Tarkka R, Uusimaa J, Alen R, Lautala P, Rantala H. Antipyretic agents for preventing recurrences of febrile seizures: randomized controlled trial. Arch Pediatr Adolesc Med 163(9): 799-804, 2009 (IF=4,320)

53. Suomalaisen Lääkäriseuran Duodecimin ja Suomen Sisätautilääkärien yhdistys ry:n asettama työryhmä: Tikkanen MJ, Strandberg T, Kesäniemi YA, Ketola E, Kovanen P, Kukkonen-Harjula K, Salo MK, Mikko Syvänne M, Vanhanen H, Jorma Viikari: Dyslipidemiat, Käypä hoito -suosituksen päivitystiivistelmä. Duodecim 125:1011-2, 2009

54. Sämpi M, Ukkola O, Päivänsalo M, Kesäniemi YA, Hörkkö S: Early atherosclerosis and IgG2 to bacteria antigens are associated with FcγRIIa genotype in non-smokers. Eur J Clin Invest 39: 517-526, 2009 (IF=2.784)

55. Ukkola O, Koivukangas V, Saarnio J, Savolainen M: Miksi diabetes paranee mahanohitusleikkauksen jälkeen?Duodecim125:233-50, 2009 Pääkirjoitus

56. Ukkola O, Kunnari A, Jokela M, Päivänsalo M, Kesäniemi YA: ApoE phenotype is associated with inflammatory markers in middle-aged subjects. Inflamm Res 58:54-59, 2009 (1,457)

57. Ukkola O, Vasunta R-L, Kesäniemi YA: Non-dipping pattern in ambulatory blood pressure monitoring is associated with metabolic abnormalities in a random sample of middle-aged subjects. Hypertens Res 32: 1022-1027, 2009 (IF=3.146)

58. Ukkola O. Onko lihavuuteen löydettävissä täsmälääkettä? Duodecim 125:817-9, 2009 Pääkirjoitus

59. Ukkola O: Gastric bypass and glucose metabolism. Intern Med J 39:502-5, 2009 (IF=1.002)

60. Ukkola O: Ghrelin and metabolic disorders. Curr Protein Pept Sci 10:2-7, 2009. Review (IF=3.011)

61. Veleva Z, Karinen P, Tomás C, Tapanainen JS, Martikainen H: Elective single embryo transfer with cryopreservation improves the outcome and diminishes the costs of IVF/ICSI. Hum Reprod 24:1632-1639, 2009 (IF=3,773)

62. Zácková T, Järvelä IY, Tapanainen JS, Feyereisl J: Assessment of endometrial and ovarian characteristics using three dimensional power Doppler ultrasound to predict response in frozen embryo transfer cycles. Reprod Biol Endocrinol 7:151-158, 2009 (IF=2,634)

Pro Gradu-tutkielmat

Meeri Keinänen: Characterization of human lung-derived fibroblastic type cells. (ohjaajat Riitta Kaarteenaho ja Siri Lehtonen) 

Väitöskirjat

Johanna Vartiainen: Ghrelin, obesity and type 2 diabetes. Genetic, metabolic and epidemiological studies. Acta Universitatis Ouluensis D 1009, 2009   

Mirella Hietaniemi: Studies on novel and traditional risk factors of atherosclerosis. Acta Universitatis Ouluensis D 1016, 2009 

Eija Kellokoski: Ghrelin and atherosclerosis. Human, experimental animal and cell culture studies. Acta Universitatis Ouluensis D 1030, 2009